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TopiCanna is a multi-use therapeutic cream formulated and manufactured under the direction of a Harvard PhD chemist with guidance from a Harvard MD.  TopiCanna’s key active ingredient, cannabidiol (CBD), is pure and potent, and it is derived exclusively from hemp.  CBD oil extracted from hemp does not produce any psychoactive effects, either when applied topically or ingested.  TopiCanna’s CBD is infused into a proprietary carrier containing rich shea butter and apricot kernel oil.  Apricot kernel oil enhances CBD’s effects through several therapeutic properties of its own:  it is an excellent emollient (moisturizer); it reduces inflammation when applied topically; and it is anti-septic and reduces risk of infection.

Studies have shown that CBD has anti-inflammatory effects and supports the body to relax muscles that are often a component of mechanical pain. While CBD does not address arthritis directly, it modifies pain by encouraging the body’s appropriate response to injury, degenerative joints, and spinal issues.

Generally within 20 minutes after TopiCanna application to the structures surrounding joints, the muscles that support the neck and back, and/or to irritated skin, people report:

  • pain reduction
  • more mobility
  • relief of itching and scaly red skin

Get the most out of your TopiCanna use: 

The best way to use TopiCanna for chronic musculoskeletal pain modulation is to rub it directly into the area that hurts–preferably after the application of wet heat (warm water). The dispenser delivers a reproducible amount that can be titrated to the severity of pain, individual response and size of area.

  • Start with 5-10 activations, but apply one dispense at a time and rub in well so that the lotion’s color and residual disappear.
  • For acute injury, at the time of the muscular injury and the 24 to 36 hours after, apply directly to the area, one activation at a time, and rub in gently, following it with application of ice with a wet washcloth that has been in the freezer for 20 minutes or a package of frozen peas

There is virtually no THC in Tropicana and no possibility of psychoactive effects or a positive drug test. It is safe for everyone to use and for treatment of all musculoskeletal pain.

Stop the pain before it even starts!

It is helpful to apply TopiCanna generously before therapeutic exercise or any activity that may cause muscular injury.

The Deadliest Deficiency


Written by Lawrence May, M.D., F.A.C.P. originally for Micro-Cap Review Magazine






By Lawrence A. May, M.D., F.A.C.P.
Chief Medical Officer, Marpella, and practicing internist.

In contrast to the fictitious Dr. McCoy (“Bones”) of Star Trek fame, we don’t have a hypospray to magically erase pain, nor do patients insist on retaining pain as part of their identity. The unvarnished reality is that many people are desperately seeking better, natural alternatives for pain control. Their basic quality of life is profoundly damaged by their pain. As a physician, I understand the pain my patients suffer, the causes, and the consequences of bad treatments. I have become convinced that cannabis can be an effective option and complement to other modalities to alleviate the pain and suffering of many people.


Pain is a universal and complex symptom and medical challenge to diagnose and treat. It can be a symptom of a serious medical problem demanding the clinician’s diagnostic expertise and requiring the clinician to acquire the patient history, perform the physical exam and order the appropriate laboratory and imaging tests. What makes pain complex and insidious is that it is subjective. The perception, intensity and demands for diagnosis and/or relief are influenced by psychology and an individual’s tolerance for discomfort. Athletes and soldiers often function with intense pain suppressed by an outpouring of neurotransmitters precipitated by the stress. Others are incapacitated and seek relief from what appear to be mild injuries that are perceived as serious or disabling. Pain provokes anxiety because chest pain is feared to be a heart attack or headache is thought to be a brain tumor.

There are two basic types of pain: nociceptive pain and neuropathic pain. Nociceptive pain is produced by obvious triggers–falling, getting hit with a baseball or touching a hot stove. These painful events of daily living provoke a normal and protective pain response. Neuropathic pain is an abnormal or harmful response caused by hypersensitivity and/or nerve damage. It may be an exaggerated response to a painful stimulus or an unpleasant reaction to a normal sensation such as temperature or touch. This dysfunctional pain is often chronic, debilitating and more challenging to treat.

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